Cerebral (Cell Region-Based Rendering And Layout) is a Java plugin for the widely
used open-source Cytoscape molecular interaction viewer. While Cytoscape offers a number of
built-in graph layout options (e.g. spring-embedded, hierarchical, circular, organic…), all of these are based on
mathematical and physical principles and do not take biological information into account. As a result, layouts do not
resemble “traditional” signaling pathway/system diagrams, which typically show interacting proteins overlaid on an image
of the cell – extracellular proteins and membrane receptors at the top, adapter proteins in the cytoplasm, and nuclear
proteins and pathway-regulated genes at the bottom.
Source : Bernard via Groupe “Cartographie d’informations” de Google Groupes